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Current Issue Table of Contents: 15 May, 2026, Volume 42, Issue 5


Impact Factor 5.8*
Journal Citation Reports Q1
(2024 CLARIVATE ANALYSTICS)

About the Cover

Although neurons have been considered the primary producers of amyloid-β (Aβ), there is increasing evidence that non-neuronal cells—such as the myelinating glia of the central nervous system, oligodendrocytes—also contribute to Aβ production in Alzheimer’s disease (AD), which is highlighted in this review by Sasmita and Depp. Understanding how non-neuronal cells process and produce Aβ may reveal novel AD preventative/therapeutic strategies to stall Aβ accumulation from reaching threshold concentrations for Aβ plaque deposition, the primary hallmark of AD. The cover depicts an investigation board with key players in Aβ pathogenesis alongside other potential cellular contributors to AD pathophysiology, centrally highlighted and connected to other aspects of AD research that have spanned over 100 years. See pages 1126–1150. (Cover designed by Andrew Octavian Sasmita).


Shumin Duan
Editor-in-Chief


Ru-Rong Ji
Co-Editor-in-Chief

Editorial Board

Editorial

Disruptions in RNA Splicing: A Key Regulator of Cognitive Impairment in Perioperative Neurocognitive Disorders
Xu‑An Wang1 · Qing‑Ya Wu2 · Xiao‑Yu Shi3 · Xiao‑Peng Wang1 · Yan‑Yan Gao1 · Wei‑Wei Zhang1 · Yi‑Sheng Lu4 · Dan Liu5 · Ling‑Qiang Zhu6 · Hua Zheng2 [SpringerLink]

ErbB4 in the Dorsolateral Prefrontal Cortex is Required for Sensory Gating and Working Memory in Monkey
Minzhe Yang1,2,6 · Yingying Han2 · Hongfei Zhang2 · Chaolin Ma2 · Lin Mei3,4,5 · Baoming Li1,2 [SpringerLink]

The Theoretical Evolution of Social Memory and the Core Contribution of the Medial Prefrontal Cortex
Tianyu Li1 · Xiaohui Zhang1 [SpringerLink]

Fat on Fire: Disrupted Microglial Lipid Metabolism as a Driver of Anesthetic Neurotoxicity
Yu‑Jie Mou1,2 · Hai‑Yue Tu3 · Yi‑Chan Wang1,2 · Shao‑Yong Song1,2 · Hua‑Yue Liu1,2,4 · Dong Wang5 · Jun‑Chao Wu6 · Xiao‑Wen Meng1,2 · Zheng‑Hong Qin6,7 · Fu‑Hai Ji1,2 [SpringerLink]

Imaging Genomics Across Primate Species: Advancing Understanding of Neurological and Psychiatric Disorders
Tingting Bo1,2,3 · Yichun Huang4 · Yong Lu2,3 · Yang Song5 · Jiangtao Zhang6 · Jianmin Zhang6 · Heqiu Wang6 · Zheng Wang4,7 [SpringerLink]

Cholesterol in Myelin: Supply Routes, Pathological Consequences, Biophysical Governance, and Future Frontiers
Xinyu Zhu1,2,3 · Fan Zhang1 · Jian Wang4 · Guannan Wang4 · Jiajia Wang1,5 [SpringerLink]

Epigenetic Tuning of TSC: A Metabolic Master Switch for Human Neocortical Expansion
Jun‑Wei Cao1 · Yinghui Fu2 [SpringerLink]

Engineered Alzheimer Organoids Validate the Link Between Intracellular and Soluble p-Tau Biomarkers and Highlight the Contribution of Astrocytic Tau
Ru Zhang1,5 · Xiaoxu Dong2 · Gang Pei1,3,4,5 · Shichao Huang1,5 [SpringerLink]

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Mesolimbic Dopaminergic Encoding of Decision Value: Linking Phenotype-Specific Signals to Strategic Adaptation
Zhengyi Xu1 · Dadao An1 · Jingjia Liang1 · Lingyan Zheng1 · Zhong Chen1 [SpringerLink]

Dorsal Column Nuclei at the Core of TENS: Circuit Principles and Outlook for Neuropathic Pain Therapy
Yi‑La Ding1 · Xue‑Qing Wu1 · Tian‑Xin Zhao1 · Shi‑Yao Wang1 · Ceng‑Lin Xu1 · Bei Tan1 · Yu Du1 [SpringerLink]

Persistence of Proliferating Neural Progenitors in the Adult Human Hippocampus: New Evidence from snRNA-seq and Machine Learning Integration
Jun‑Wei Cao1 · Bing Lang2 [SpringerLink]

Astrocytes Control Norepinephrine Signaling in the Brain
Hai‑Yun Xiong1 · Peter Illes1,2 · Yong Tang1 [SpringerLink]

Subparafascicular Thalamic Nucleus: An Integration Center for Sexual Motivation and Physical Contact in Mating Behaviour
Siyuan Li1,2 · Xinrong Wang1,5 · Junqiang Zheng1,5 · Han Xu1,2,3,4,5 [SpringerLink]

Beyond the Glial Scar: Fibroblasts as Dynamic Coordinators of Neuroprotection and Neuroinflammation Post-Brain Injury
Xinjie Hong1,2 · Xiaoyong Qin2 · Lijun Hou1 [SpringerLink]

Putting the Brakes on Thirst: A Neural Circuit for Anticipatory Fluid Control
Boli Fu1,2 · Qiujie Shi1 · Qin Wang1 [SpringerLink]

Serpine2-Lrp1 and CD39-A3AR Intercellular Signalling Pathways: Novel Therapeutic Targets for Vascular Dementia
Xiao‑Feng Ran1 · Peter Illes1,2 · Yong Tang1 [SpringerLink]

Beyond Amyloid: Stem Cell Therapy Targets Neurodegeneration in Alzheimer’s Disease
Chenyue Li1 · Qiyi Hu1 · Qing Wang1,2,3 · Chunming Xie1,2,3 [SpringerLink]

The Thalamic Reticular Ultimatum: Carbamazepine’s Betrayal in Absence Epileptic Seizures
Xiongfeng Guo1 · Yuanzhi Yang1 · Junxiu Ye1 · Xiangyu Ma1 · Tong Liu1 · Kai Zhong2 · Cenglin Xu1 [SpringerLink]

Neural-Activity-Regulated Development of Meningeal Lymphatic System in Zebrafish: Novel Mechanism of Brain Self-Cleaning and Neuroimmune Regulation
Guangdong Liu1 · Weidong Le1 [SpringerLink]

Dual Transmitter Oscillations for Ejaculation
Anqi Wei1 · Shuqin Zhan1 · Hong Fan1 · Huadong Xu1 · Xinjiang Kang2,3 · Changhe Wang1,2,3 [SpringerLink]

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Targeting Microglial Connexin43 Hemichannels: A Novel Therapeutic Avenue for Alzheimer’s Disease
Chenju Yi1,2,3,4 · Yixun Su1 · Alexei Verkhratsky3,5,6,7,8 [SpringerLink]

Photobiomodulation and Addiction: Exploring Mechanisms, Therapeutic Potential, and Future Directions in Substance Use Disorders
Xiujiao Qin1 · Hongyuan Li2 · Huiying Zhao1 · Xiaohui Wang2,3,4 [SpringerLink]

IL-17 as a New Player in Neuroimmune Cross-Talk: Rewiring Behaviors Through Cytokine-Receptor Cartography
Jinmei Ye1 · Lan Yan2 · Zhibo Tang2 · Jiashuo Xu1 · Jie Weng2 · Tifei Yuan2,3 · Daihui Peng1 [SpringerLink]

Preparatory Activity Indexes Motor Memory in the Motor Cortex
Xiao–Lin Shen1,2,3 · He–Xin Zhao1,2,3 · Yu–Hao Xiao1,2,3 · Yong–Xiang Wang1,4,5 · Li–Zhang Zeng2,3 · Hong–Yan Geng1,6 [SpringerLink]

Electrochemical Detection of Oxytocin: Challenges and Prospects
Jiao Zhang1 · Xiaojian Li2,3,4 · Ji Dai2,3,4 [SpringerLink]

Targeting Microglial Connexin43 Hemichannels: A Novel Therapeutic Avenue for Alzheimer’s Disease
Chenju Yi1,2,3,4 · Yixun Su1 · Alexei Verkhratsky3,5,6,7,8 [SpringerLink]

Psilocybin and Obsessive-Compulsive Disorder: Exploring New Therapeutic Horizons
Longwei Yang1,2 · Haohong Li3,4 · Xiaohui Wang1,2,4 [SpringerLink]

Exploring the Therapeutic Potential of Psychedelics in Chronic Pain Management: A New Frontier in Medicine
Cong Lin1 · Xue Wang2 · Xiaohui Wang1,3 [SpringerLink]

Halting the Progression of Alzheimer’s Disease: Is the Goal in Sight?
Yu‑Juan Jia1,2 · Xuan‑Yue Wang3 · Jie Liu2 · Yan‑Jiang Wang4,5 · Colin L. Masters6 · Jun‑Hong Guo1 [SpringerLink]

The Current State and Future Outlook of PET Tracers for AMPA Receptors
Ling Li1 · Shenglin Wen1 · Ji Dai2,3,4,5 [SpringerLink]

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The Risk and Prevention of Novel Coronavirus Pneumonia Infections Among Inpatients in Psychiatric Hospitals
Yuncheng Zhu • Liangliang Chen • Haifeng Ji • Maomao Xi • Yiru Fang • Yi Li [SpringerLink]

Expert Consensus on the Care and Management of Patients with Cognitive Impairment in China
Academy of Cognitive Disorders of China (ACDC) • Yuliang Han • Jianjun Jia • Xia Li • Yang Lv • Xuan Sun • Shanshan Wang • Yongjun Wang • Zhiwen Wang • Jintao Zhang • Jiong Zhou & Yuying Zhou [SpringerLink]

An Overview of the Expert Consensus on the Prevention and Treatment of Gaming Disorder in China (2019 Edition)
Yu-Tao Xiang • Yu Jin • Ling Zhang • Lu Li • Gabor S. Ungvari • Chee H. Ng • Min Zhao & Wei Hao [SpringerLink]

Perspective on Etiology and Treatment of Bipolar Disorders in China: Clinical Implications and Future Directions
Zuowei Wang • Chen Jun • Keming Gao • Haichen Yang • Yiru Fang [SpringerLink]

Standardized Operational Protocol for Human Brain Banking in China
Wenying Qiu • Hanlin Zhang • Aimin Bao • Keqing Zhu • Yue Huang • Xiaoxin Yan • Jing Zhang • Chunjiu Zhong • Yong Shen • Jiangning Zhou • Xiaoying Zheng • Liwei Zhang • Yousheng Shu • Beisha Tang • Zhenxin Zhang • Gang Wang • Ren Zhou • Bing Sun • Changlin Gong • Shumin Duan & Chao Ma [SpringerLink]

Impaired Hypothalamic Regulation of Sympathetic Outflow in Primary Hypertension
Jing-Jing Zhou • Hui-Jie Ma • Jian-Ying Shao • Hui-Lin Pan • De-Pei Li [SpringerLink]

The Risk and Prevention of Novel Coronavirus Pneumonia Infections Among Inpatients in Psychiatric Hospitals
Yuncheng Zhu 1 • Liangliang Chen 2 • Haifeng Ji 2 • Maomao Xi 3 • Yiru Fang 1,5,6 • Yi Li 4 [SpringerLink]

An Overview of Autism Spectrum Disorder, Heterogeneity and Treatment Options OPEN ACCESS
Anne Masi1 • Marilena M. DeMayo1 • Nicholas Glozier1 • Adam J. Guastella1 [SpringerLink]

Pharmacological Modulation of Vagal Nerve Activity in Cardiovascular Diseases
Longzhu Liu • Ming Zhao • Xiaojiang Yu • Weijin Zang* [SpringerLink]

Gene Editing to the Rescue: Reversal of Social Deficits Associated with MECP2 Duplication
Zi-Xian Yu 1,2,3 • Dan-Yang Wang 1,2,3 • Xiao-Hong Xu 1,3 [SpringerLink]

Regulation of Pain and Itch by TRP Channels
Carlene Moore1 • Rupali Gupta1 • Sven-Eric Jordt2 • Yong Chen1,* • Wolfgang B. Liedtke1,2,* [SpringerLink]

Spinal Circuits Transmitting Mechanical Pain and Itch
Bo Duan1,* • Longzhen Cheng2,* • Qiufu Ma3,* [SpringerLink]

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Special Issue on Pain and Itch
Issue Editor: Ru-Rong Ji
2025 Vol 41 Issue 12

[PDF] [SpringerLink]

Special Issue Celebrating the 25th Anniversary of the Institute of Neuroscience, CAS
Issue Editors: ting lv,Fei Dong,Shumin Duan,Yefei Li
2024 Vol 40 Issue 11

[PDF] [SpringerLink]

Special Issue on Novel Mechanism, Drug Target and Therapy in Epilepsy
Issue Editor: Zhong Chen
2024 Vol 40 Issue 5

[PDF] [SpringerLink]

Special Issue on Novel Insight into Glial Biology and Diseases
Issue editor: He Cheng
2023 Vol 39 Issue 3

[PDF] [SpringerLink]

Special Issue on Pain and Itch
Guest Editor: Ru-Rong Ji
2022 Vol 38 Issue 4

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