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Current Issue Table of Contents: 15 August, 2026, Volume 42, Issue 8


Impact Factor 6.8*
Journal Citation Reports Q1
(2025 CLARIVATE ANALYSTICS)

About the Cover

How does past social experience shape future behavior? In this issue, Wang et al. reveal how cross-species encounters serve as a natural peacemaker for Drosophila. This adaptive behavior is dynamic: prolonged cross-species experience enhances suppression of aggression, while social isolation reverses it. The artwork illustrates a male D. melanogaster on a contested food patch alongside a closely related D. simulans and a distantly related D. virilis. Glowing elements highlight the integration of multisensory cues that persistently tune down aggression across different timescales. Flies detect non-volatile cues such as 7-T (yellow) through leg-mediated gustation to enable rapid behavioral shifts, while processing volatile pheromones such as cVA (purple) via antennal olfaction for slower modulation. Deep within the head of D. melanogaster, a body-brain circuit integrates multisensory inputs into P1 neurons, which act as a leaky integrator to record cross-species interactions and dampen the urge to fight. The artwork captures an elegant evolutionary strategy: dialing back unnecessary aggression to conserve vital energy. See pages 1691–1705. (Cover designed by Junlong Wang and Yi Sun)



Shumin Duan
Editor-in-Chief


Ru-Rong Ji
Co-Editor-in-Chief

Editorial Board

Editorial

Astrocytic Prostaglandin Transporter SLCO2A1–Ca2+ Maintains Blood–Brain Barrier Integrity Against Ischemia
Taozhi Wang1,2,3 · Manping Yang2,3 · Haiyun Guo1 · Hongyu Ma2,3,4,5 · Zhenzhen Li2,3 · Junjun Kang2,3 · Yaomin Guo6 · Shengxi Wu2,3 · Yazhou Wang2,3 · Wugang Hou1,7 [SpringerLink]

Tuning Rather Than Replacing: MECP2 Isoform Switching Opens a New Therapeutic Avenue for Rett Syndrome
Xue Liu1 · Ling Gong2 · Miao He2 [SpringerLink]

Rebooting the Dialogue: Neuromodulation for Immune-Driven Brain-Body Interactions in Post-stroke Emotional Disorders
Yuan Liu1 · Chengxin Ji1 · Shujing Li2,3 · Zhengrun Gao1,2,3 [SpringerLink]

Nucleus Accumbens D1 Receptor Neurons Contribute to Emotional and Metabolic Adaptation to Chronic Hypoxia
Yan Chen1,2 · Jie Shao1 · Lu Zhang1 · Yuchuan Hong1 · Hao Yang3 · Shirui Jun1 · William Weijia Lu4 · Jie Tu1,6 · Guoxin Ni5 · Fan Yang1 [SpringerLink]

Cocaine Hijacks the Npas4-dependent Somatostatin Ensembles in the mPFC to Mediate Attention
Xutian Hou1 · Kunxiu Han1 · Feifei Wang1,2 · Changyou Jiang1 · Lan Ma1 · Tao Jin1 [SpringerLink]

Deep Brain Stimulation for Disorders of Consciousness: From Mesocircuit Mechanisms to Circuit-Guided Precision Neuromodulation
Di Zang1 · Keiko Hasuike3 · Zengxin Qi4 · Yanbing Yu1 · Peng Gui2 [SpringerLink]

State-Dependent Modulation of a Theta-Responsive Subnetwork by High-Frequency Stimulation of the Ventral Striatum
Wenlei Zhang1 · Xiaotian Wu1 · Chengjie Tang1 · Weicong Sang1 · Yujian Ye1 · Hong Gan1,2 · Tianzhen Chen1 · Ti‑Fei Yuan1,3 · Rongwei Zhai4 · Haifeng Jiang1 · Zhi‑Qi Xiong5 · Min Zhao1 [SpringerLink]

Decoding the Oxytocinergic and Behavioral Signatures of Milk Ejection
Wei Xiao1,2,3 · Qian Zheng2,4 · Yang Wang2,4 · Ying Yuan1,2,3 · Yuge Chen1,2,3 · Tianxing Zheng5 · Yuzhu Chen1 · Yijia Gao6 · Bingrui Song1 · Bin Zhang1,2,3 · Liyao Qiu1,2,3 · Linghui Zeng7 · Huan Ma1,2,3,8 · Colin H. Brown9 · Shumin Duan1,2,3 · Gang Pan2,4 · Zhihua Gao1,2,3 [SpringerLink]

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Epigenetic Tuning of TSC: A Metabolic Master Switch for Human Neocortical Expansion
Jun‑Wei Cao1 · Yinghui Fu2 [SpringerLink]

Beyond the Seizure Onset Zone: Fast Ripples as Anchors for Precise Neurostimulation Therapy
Shuye Ying1 · Jialu Chen2 · Xukun Fan1 · Yi Wang1 · Fan Fei1 [SpringerLink]

Mesolimbic Dopaminergic Encoding of Decision Value: Linking Phenotype-Specific Signals to Strategic Adaptation
Zhengyi Xu1 · Dadao An1 · Jingjia Liang1 · Lingyan Zheng1 · Zhong Chen1 [SpringerLink]

Dorsal Column Nuclei at the Core of TENS: Circuit Principles and Outlook for Neuropathic Pain Therapy
Yi‑La Ding1 · Xue‑Qing Wu1 · Tian‑Xin Zhao1 · Shi‑Yao Wang1 · Ceng‑Lin Xu1 · Bei Tan1 · Yu Du1 [SpringerLink]

Persistence of Proliferating Neural Progenitors in the Adult Human Hippocampus: New Evidence from snRNA-seq and Machine Learning Integration
Jun‑Wei Cao1 · Bing Lang2 [SpringerLink]

Astrocytes Control Norepinephrine Signaling in the Brain
Hai‑Yun Xiong1 · Peter Illes1,2 · Yong Tang1 [SpringerLink]

Subparafascicular Thalamic Nucleus: An Integration Center for Sexual Motivation and Physical Contact in Mating Behaviour
Siyuan Li1,2 · Xinrong Wang1,5 · Junqiang Zheng1,5 · Han Xu1,2,3,4,5 [SpringerLink]

Beyond the Glial Scar: Fibroblasts as Dynamic Coordinators of Neuroprotection and Neuroinflammation Post-Brain Injury
Xinjie Hong1,2 · Xiaoyong Qin2 · Lijun Hou1 [SpringerLink]

Putting the Brakes on Thirst: A Neural Circuit for Anticipatory Fluid Control
Boli Fu1,2 · Qiujie Shi1 · Qin Wang1 [SpringerLink]

Serpine2-Lrp1 and CD39-A3AR Intercellular Signalling Pathways: Novel Therapeutic Targets for Vascular Dementia
Xiao‑Feng Ran1 · Peter Illes1,2 · Yong Tang1 [SpringerLink]

Beyond Amyloid: Stem Cell Therapy Targets Neurodegeneration in Alzheimer’s Disease
Chenyue Li1 · Qiyi Hu1 · Qing Wang1,2,3 · Chunming Xie1,2,3 [SpringerLink]

The Thalamic Reticular Ultimatum: Carbamazepine’s Betrayal in Absence Epileptic Seizures
Xiongfeng Guo1 · Yuanzhi Yang1 · Junxiu Ye1 · Xiangyu Ma1 · Tong Liu1 · Kai Zhong2 · Cenglin Xu1 [SpringerLink]

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Targeting Microglial Connexin43 Hemichannels: A Novel Therapeutic Avenue for Alzheimer’s Disease
Chenju Yi1,2,3,4 · Yixun Su1 · Alexei Verkhratsky3,5,6,7,8 [SpringerLink]

Photobiomodulation and Addiction: Exploring Mechanisms, Therapeutic Potential, and Future Directions in Substance Use Disorders
Xiujiao Qin1 · Hongyuan Li2 · Huiying Zhao1 · Xiaohui Wang2,3,4 [SpringerLink]

IL-17 as a New Player in Neuroimmune Cross-Talk: Rewiring Behaviors Through Cytokine-Receptor Cartography
Jinmei Ye1 · Lan Yan2 · Zhibo Tang2 · Jiashuo Xu1 · Jie Weng2 · Tifei Yuan2,3 · Daihui Peng1 [SpringerLink]

Preparatory Activity Indexes Motor Memory in the Motor Cortex
Xiao–Lin Shen1,2,3 · He–Xin Zhao1,2,3 · Yu–Hao Xiao1,2,3 · Yong–Xiang Wang1,4,5 · Li–Zhang Zeng2,3 · Hong–Yan Geng1,6 [SpringerLink]

Electrochemical Detection of Oxytocin: Challenges and Prospects
Jiao Zhang1 · Xiaojian Li2,3,4 · Ji Dai2,3,4 [SpringerLink]

Targeting Microglial Connexin43 Hemichannels: A Novel Therapeutic Avenue for Alzheimer’s Disease
Chenju Yi1,2,3,4 · Yixun Su1 · Alexei Verkhratsky3,5,6,7,8 [SpringerLink]

Psilocybin and Obsessive-Compulsive Disorder: Exploring New Therapeutic Horizons
Longwei Yang1,2 · Haohong Li3,4 · Xiaohui Wang1,2,4 [SpringerLink]

Exploring the Therapeutic Potential of Psychedelics in Chronic Pain Management: A New Frontier in Medicine
Cong Lin1 · Xue Wang2 · Xiaohui Wang1,3 [SpringerLink]

Halting the Progression of Alzheimer’s Disease: Is the Goal in Sight?
Yu‑Juan Jia1,2 · Xuan‑Yue Wang3 · Jie Liu2 · Yan‑Jiang Wang4,5 · Colin L. Masters6 · Jun‑Hong Guo1 [SpringerLink]

The Current State and Future Outlook of PET Tracers for AMPA Receptors
Ling Li1 · Shenglin Wen1 · Ji Dai2,3,4,5 [SpringerLink]

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The Risk and Prevention of Novel Coronavirus Pneumonia Infections Among Inpatients in Psychiatric Hospitals
Yuncheng Zhu • Liangliang Chen • Haifeng Ji • Maomao Xi • Yiru Fang • Yi Li [SpringerLink]

Expert Consensus on the Care and Management of Patients with Cognitive Impairment in China
Academy of Cognitive Disorders of China (ACDC) • Yuliang Han • Jianjun Jia • Xia Li • Yang Lv • Xuan Sun • Shanshan Wang • Yongjun Wang • Zhiwen Wang • Jintao Zhang • Jiong Zhou & Yuying Zhou [SpringerLink]

An Overview of the Expert Consensus on the Prevention and Treatment of Gaming Disorder in China (2019 Edition)
Yu-Tao Xiang • Yu Jin • Ling Zhang • Lu Li • Gabor S. Ungvari • Chee H. Ng • Min Zhao & Wei Hao [SpringerLink]

Perspective on Etiology and Treatment of Bipolar Disorders in China: Clinical Implications and Future Directions
Zuowei Wang • Chen Jun • Keming Gao • Haichen Yang • Yiru Fang [SpringerLink]

Standardized Operational Protocol for Human Brain Banking in China
Wenying Qiu • Hanlin Zhang • Aimin Bao • Keqing Zhu • Yue Huang • Xiaoxin Yan • Jing Zhang • Chunjiu Zhong • Yong Shen • Jiangning Zhou • Xiaoying Zheng • Liwei Zhang • Yousheng Shu • Beisha Tang • Zhenxin Zhang • Gang Wang • Ren Zhou • Bing Sun • Changlin Gong • Shumin Duan & Chao Ma [SpringerLink]

Impaired Hypothalamic Regulation of Sympathetic Outflow in Primary Hypertension
Jing-Jing Zhou • Hui-Jie Ma • Jian-Ying Shao • Hui-Lin Pan • De-Pei Li [SpringerLink]

The Risk and Prevention of Novel Coronavirus Pneumonia Infections Among Inpatients in Psychiatric Hospitals
Yuncheng Zhu 1 • Liangliang Chen 2 • Haifeng Ji 2 • Maomao Xi 3 • Yiru Fang 1,5,6 • Yi Li 4 [SpringerLink]

An Overview of Autism Spectrum Disorder, Heterogeneity and Treatment Options OPEN ACCESS
Anne Masi1 • Marilena M. DeMayo1 • Nicholas Glozier1 • Adam J. Guastella1 [SpringerLink]

Pharmacological Modulation of Vagal Nerve Activity in Cardiovascular Diseases
Longzhu Liu • Ming Zhao • Xiaojiang Yu • Weijin Zang* [SpringerLink]

Gene Editing to the Rescue: Reversal of Social Deficits Associated with MECP2 Duplication
Zi-Xian Yu 1,2,3 • Dan-Yang Wang 1,2,3 • Xiao-Hong Xu 1,3 [SpringerLink]

Regulation of Pain and Itch by TRP Channels
Carlene Moore1 • Rupali Gupta1 • Sven-Eric Jordt2 • Yong Chen1,* • Wolfgang B. Liedtke1,2,* [SpringerLink]

Spinal Circuits Transmitting Mechanical Pain and Itch
Bo Duan1,* • Longzhen Cheng2,* • Qiufu Ma3,* [SpringerLink]

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Special Issue on Pain and Itch
Issue Editor: Ru-Rong Ji
2025 Vol 41 Issue 12

[PDF] [SpringerLink]

Special Issue Celebrating the 25th Anniversary of the Institute of Neuroscience, CAS
Issue Editors: ting lv,Fei Dong,Shumin Duan,Yefei Li
2024 Vol 40 Issue 11

[PDF] [SpringerLink]

Special Issue on Novel Mechanism, Drug Target and Therapy in Epilepsy
Issue Editor: Zhong Chen
2024 Vol 40 Issue 5

[PDF] [SpringerLink]

Special Issue on Novel Insight into Glial Biology and Diseases
Issue editor: He Cheng
2023 Vol 39 Issue 3

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Special Issue on Pain and Itch
Guest Editor: Ru-Rong Ji
2022 Vol 38 Issue 4

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