We suggest you to use the updated system or browser for the best display of the new website.


Current Issue Table of Contents: 15 September, 2026, Volume 42, Issue 9


Impact Factor 6.8*
Journal Citation Reports Q1
(2025 CLARIVATE ANALYSTICS)

About the Cover

Deep brain stimulation (DBS) is emerging as a potential strategy for restoring arousal and functional communication in carefully selected patients with disorders of consciousness. Zang et al. integrate mesocircuit mechanisms, connectome-guided targeting, cognitive–motor dissociation, and adaptive neuromodulation to chart a path from experimental stimulation toward circuit-guided precision therapy. On the cover, a mist-shrouded pine forest forms the folds of the cerebral cortex, evoking a brain whose pathways of communication have become obscured after severe injury. At its center, paired luminous roots symbolize the central thalamus, while a warm beam of DBS light represents re-engagement of the anterior forebrain mesocircuit. Firefly-like signals trace a narrow route through the forest, representing renewed cortico-striato-thalamo-cortical communication. The solitary figure following this path embodies covert consciousness and the cautious possibility of re-emerging from silence into meaningful interaction. See pages 2057–2075. (Cover designed by Di Zang & Peng Gui)




Shumin Duan
Editor-in-Chief


Ru-Rong Ji
Co-Editor-in-Chief

Editorial Board

Editorial

From Multisensory Integration to Decision Execution: Computational Roles of the Posterior Parietal Cortex in Mice
Zhenning Lv1 · Yu Gu1 [SpringerLink]

Evolution and Reorganization of the Hierarchical Brain-wide Neuronal Network Through Anesthesia
Hong‑Jing Chen1 · Mei‑Ting Zhao2 · Zhi‑Feng Lv2 · Jie Hao2 · Wen‑Jie Du3 · Chun‑Feng Shang1,4,5 [SpringerLink]

Vagal PIEZO2-Positive Neurons Mediate Blood Volume Sensing and Circulatory Homeostasis Regulation
Xingying Wu1,2 · Yawen Huang3 · Han Xu1,2,4,5,6 [SpringerLink]

Speech Brain-Computer Interfaces: A New Pathway for Restoring Communication in Anarthria
Lei Deng1 · Fenglian Li2 · Ming Song2,3,4,5 [SpringerLink]

Functional Dissociation of Anterior Cingulate Cortex Excitatory and Inhibitory Neurons in Sustained Attention and Impulse Control
Youming Tan1,3 · Ruonan Li2,3 · Zifu Kong3 · Yin Yue3 · Zengqiang Yuan1,2,3 [SpringerLink]

Expanded Polyglycine Protein Aggregates Alter the RNA Splicing Profile into a Premature State Partially via Sequestering SF3B4
Jiaxin Yang1 · Youqi Zheng1 · Jianyi Hu1 · Yanzhen Wu1 · Xin Yang1 · Peihan Chai1 · Zhaolin Zhang1 · Shiping Zhang1 · Qiong Liu2 · Yongcheng Pan2 · Yimin Sun3 · Jian Wang3 · Beisha Tang2 · Boxun Lu1 · Huijuan Feng1,4,5 · Yuhua Fu1 [SpringerLink]

Identification of Age-Associated Upstream Regulators to Promote Neuronal Resilience in HD Patient-Derived Neurons
Young Mi Oh1 · Emily A. Bacallao1 · Shin‑Ae Lee1 · Jihyun Kim1 · Samuel Swinford1 · Genevieve E. Smith2 · Bryce Britt1 · Shaymaa Madbouli Abdalla1 · Seong Won Lee1 [SpringerLink]

Aberrant Gamma Oscillations in Parkinson’s Disease
Bing‑Yu Li1 · Ruo‑Yu Li1,2 · Rong‑Hua Hong1,2 · Yun‑Ping Song1 · Ling‑Jing Jin1,2,3,4 [SpringerLink]

Read more...


Epigenetic Tuning of TSC: A Metabolic Master Switch for Human Neocortical Expansion
Jun‑Wei Cao1 · Yinghui Fu2 [SpringerLink]

Beyond the Seizure Onset Zone: Fast Ripples as Anchors for Precise Neurostimulation Therapy
Shuye Ying1 · Jialu Chen2 · Xukun Fan1 · Yi Wang1 · Fan Fei1 [SpringerLink]

Mesolimbic Dopaminergic Encoding of Decision Value: Linking Phenotype-Specific Signals to Strategic Adaptation
Zhengyi Xu1 · Dadao An1 · Jingjia Liang1 · Lingyan Zheng1 · Zhong Chen1 [SpringerLink]

Dorsal Column Nuclei at the Core of TENS: Circuit Principles and Outlook for Neuropathic Pain Therapy
Yi‑La Ding1 · Xue‑Qing Wu1 · Tian‑Xin Zhao1 · Shi‑Yao Wang1 · Ceng‑Lin Xu1 · Bei Tan1 · Yu Du1 [SpringerLink]

Persistence of Proliferating Neural Progenitors in the Adult Human Hippocampus: New Evidence from snRNA-seq and Machine Learning Integration
Jun‑Wei Cao1 · Bing Lang2 [SpringerLink]

Astrocytes Control Norepinephrine Signaling in the Brain
Hai‑Yun Xiong1 · Peter Illes1,2 · Yong Tang1 [SpringerLink]

Subparafascicular Thalamic Nucleus: An Integration Center for Sexual Motivation and Physical Contact in Mating Behaviour
Siyuan Li1,2 · Xinrong Wang1,5 · Junqiang Zheng1,5 · Han Xu1,2,3,4,5 [SpringerLink]

Beyond the Glial Scar: Fibroblasts as Dynamic Coordinators of Neuroprotection and Neuroinflammation Post-Brain Injury
Xinjie Hong1,2 · Xiaoyong Qin2 · Lijun Hou1 [SpringerLink]

Putting the Brakes on Thirst: A Neural Circuit for Anticipatory Fluid Control
Boli Fu1,2 · Qiujie Shi1 · Qin Wang1 [SpringerLink]

Serpine2-Lrp1 and CD39-A3AR Intercellular Signalling Pathways: Novel Therapeutic Targets for Vascular Dementia
Xiao‑Feng Ran1 · Peter Illes1,2 · Yong Tang1 [SpringerLink]

Beyond Amyloid: Stem Cell Therapy Targets Neurodegeneration in Alzheimer’s Disease
Chenyue Li1 · Qiyi Hu1 · Qing Wang1,2,3 · Chunming Xie1,2,3 [SpringerLink]

The Thalamic Reticular Ultimatum: Carbamazepine’s Betrayal in Absence Epileptic Seizures
Xiongfeng Guo1 · Yuanzhi Yang1 · Junxiu Ye1 · Xiangyu Ma1 · Tong Liu1 · Kai Zhong2 · Cenglin Xu1 [SpringerLink]

Read more...

Targeting Microglial Connexin43 Hemichannels: A Novel Therapeutic Avenue for Alzheimer’s Disease
Chenju Yi1,2,3,4 · Yixun Su1 · Alexei Verkhratsky3,5,6,7,8 [SpringerLink]

Photobiomodulation and Addiction: Exploring Mechanisms, Therapeutic Potential, and Future Directions in Substance Use Disorders
Xiujiao Qin1 · Hongyuan Li2 · Huiying Zhao1 · Xiaohui Wang2,3,4 [SpringerLink]

IL-17 as a New Player in Neuroimmune Cross-Talk: Rewiring Behaviors Through Cytokine-Receptor Cartography
Jinmei Ye1 · Lan Yan2 · Zhibo Tang2 · Jiashuo Xu1 · Jie Weng2 · Tifei Yuan2,3 · Daihui Peng1 [SpringerLink]

Preparatory Activity Indexes Motor Memory in the Motor Cortex
Xiao–Lin Shen1,2,3 · He–Xin Zhao1,2,3 · Yu–Hao Xiao1,2,3 · Yong–Xiang Wang1,4,5 · Li–Zhang Zeng2,3 · Hong–Yan Geng1,6 [SpringerLink]

Electrochemical Detection of Oxytocin: Challenges and Prospects
Jiao Zhang1 · Xiaojian Li2,3,4 · Ji Dai2,3,4 [SpringerLink]

Targeting Microglial Connexin43 Hemichannels: A Novel Therapeutic Avenue for Alzheimer’s Disease
Chenju Yi1,2,3,4 · Yixun Su1 · Alexei Verkhratsky3,5,6,7,8 [SpringerLink]

Psilocybin and Obsessive-Compulsive Disorder: Exploring New Therapeutic Horizons
Longwei Yang1,2 · Haohong Li3,4 · Xiaohui Wang1,2,4 [SpringerLink]

Exploring the Therapeutic Potential of Psychedelics in Chronic Pain Management: A New Frontier in Medicine
Cong Lin1 · Xue Wang2 · Xiaohui Wang1,3 [SpringerLink]

Halting the Progression of Alzheimer’s Disease: Is the Goal in Sight?
Yu‑Juan Jia1,2 · Xuan‑Yue Wang3 · Jie Liu2 · Yan‑Jiang Wang4,5 · Colin L. Masters6 · Jun‑Hong Guo1 [SpringerLink]

The Current State and Future Outlook of PET Tracers for AMPA Receptors
Ling Li1 · Shenglin Wen1 · Ji Dai2,3,4,5 [SpringerLink]

Read more...

The Risk and Prevention of Novel Coronavirus Pneumonia Infections Among Inpatients in Psychiatric Hospitals
Yuncheng Zhu • Liangliang Chen • Haifeng Ji • Maomao Xi • Yiru Fang • Yi Li [SpringerLink]

Expert Consensus on the Care and Management of Patients with Cognitive Impairment in China
Academy of Cognitive Disorders of China (ACDC) • Yuliang Han • Jianjun Jia • Xia Li • Yang Lv • Xuan Sun • Shanshan Wang • Yongjun Wang • Zhiwen Wang • Jintao Zhang • Jiong Zhou & Yuying Zhou [SpringerLink]

An Overview of the Expert Consensus on the Prevention and Treatment of Gaming Disorder in China (2019 Edition)
Yu-Tao Xiang • Yu Jin • Ling Zhang • Lu Li • Gabor S. Ungvari • Chee H. Ng • Min Zhao & Wei Hao [SpringerLink]

Perspective on Etiology and Treatment of Bipolar Disorders in China: Clinical Implications and Future Directions
Zuowei Wang • Chen Jun • Keming Gao • Haichen Yang • Yiru Fang [SpringerLink]

Standardized Operational Protocol for Human Brain Banking in China
Wenying Qiu • Hanlin Zhang • Aimin Bao • Keqing Zhu • Yue Huang • Xiaoxin Yan • Jing Zhang • Chunjiu Zhong • Yong Shen • Jiangning Zhou • Xiaoying Zheng • Liwei Zhang • Yousheng Shu • Beisha Tang • Zhenxin Zhang • Gang Wang • Ren Zhou • Bing Sun • Changlin Gong • Shumin Duan & Chao Ma [SpringerLink]

Impaired Hypothalamic Regulation of Sympathetic Outflow in Primary Hypertension
Jing-Jing Zhou • Hui-Jie Ma • Jian-Ying Shao • Hui-Lin Pan • De-Pei Li [SpringerLink]

The Risk and Prevention of Novel Coronavirus Pneumonia Infections Among Inpatients in Psychiatric Hospitals
Yuncheng Zhu 1 • Liangliang Chen 2 • Haifeng Ji 2 • Maomao Xi 3 • Yiru Fang 1,5,6 • Yi Li 4 [SpringerLink]

An Overview of Autism Spectrum Disorder, Heterogeneity and Treatment Options OPEN ACCESS
Anne Masi1 • Marilena M. DeMayo1 • Nicholas Glozier1 • Adam J. Guastella1 [SpringerLink]

Pharmacological Modulation of Vagal Nerve Activity in Cardiovascular Diseases
Longzhu Liu • Ming Zhao • Xiaojiang Yu • Weijin Zang* [SpringerLink]

Gene Editing to the Rescue: Reversal of Social Deficits Associated with MECP2 Duplication
Zi-Xian Yu 1,2,3 • Dan-Yang Wang 1,2,3 • Xiao-Hong Xu 1,3 [SpringerLink]

Regulation of Pain and Itch by TRP Channels
Carlene Moore1 • Rupali Gupta1 • Sven-Eric Jordt2 • Yong Chen1,* • Wolfgang B. Liedtke1,2,* [SpringerLink]

Spinal Circuits Transmitting Mechanical Pain and Itch
Bo Duan1,* • Longzhen Cheng2,* • Qiufu Ma3,* [SpringerLink]

Read more...


Special Issue on Pain and Itch
Issue Editor: Ru-Rong Ji
2025 Vol 41 Issue 12

[PDF] [SpringerLink]

Special Issue Celebrating the 25th Anniversary of the Institute of Neuroscience, CAS
Issue Editors: ting lv,Fei Dong,Shumin Duan,Yefei Li
2024 Vol 40 Issue 11

[PDF] [SpringerLink]

Special Issue on Novel Mechanism, Drug Target and Therapy in Epilepsy
Issue Editor: Zhong Chen
2024 Vol 40 Issue 5

[PDF] [SpringerLink]

Special Issue on Novel Insight into Glial Biology and Diseases
Issue editor: He Cheng
2023 Vol 39 Issue 3

[PDF] [SpringerLink]

Special Issue on Pain and Itch
Guest Editor: Ru-Rong Ji
2022 Vol 38 Issue 4

[PDF] [SpringerLink]

Read more...