Volume 35, Issue. 1, February, 2019


Editorial

Autonomic Regulation of the Cardiovascular System: Diseases, Treatments, and Novel Approaches 
Zixi Jack Cheng• Renjun Wang• Qing-Hui Chen
2019, 35(1): 1-3   [ Abstract]   [ SpringerLink]

Original Articles

Neonatal Maternal Deprivation Followed by Adult Stress Enhances Adrenergic Signaling to Advance Visceral Hypersensitivity
Wan-Jie Du • Shufen Hu • Xin Li • Ping-An Zhang • Xinghong Jiang • Shan-Ping Yu • Guang-Yin Xu
2019, 35(1): 4-14   [ Abstract]   [ SpringerLink]

Anti-Hypertensive Action of Fenofibrate via UCP2 Upregulation Mediated by PPAR Activation in Baroreflex Afferent Pathway
Jian Guan • Miao Zhao • Chao He • Xue Li • Ying Li • Jie Sun • Wei Wang • Ya-Li Cui • Qing Zhang • Bai-Yan Li • Guo-Fen Qiao
2019, 35(1): 15-24   [ Abstract]   [ SpringerLink]

Decreased β-Cell Function is Associated with Cardiovascular Autonomic Neuropathy in Chinese Patients Newly Diagnosed with Type 2 Diabetes
Xubin Yang • Wen Xu • Yanhua Zhu • Hongrong Deng • Ying Tan • Longyi Zeng • Jianping Weng
2019, 35(1): 25-33   [ Abstract]   [ SpringerLink]

Intermedin in Paraventricular Nucleus Attenuates Sympathoexcitation and Decreases TLR4-Mediated Sympathetic Activation via Adrenomedullin Receptors in Rats with Obesity-Related Hypertension
Jing Sun • Xing-Sheng Ren • Ying Kang • Hang-Bing Dai • Lei Ding • Ning Tong • Guo-Qing Zhu • Ye-Bo Zhou
2019, 35(1): 34-46   [ Abstract]   [ SpringerLink]

Blockade of Endogenous Angiotensin-(1–7) in Hypothalamic Paraventricular Nucleus Attenuates High Salt-Induced Sympathoexcitation and Hypertension
Xiao-Jing Yu • Yu-Wang Miao • Hong-Bao Li • Qing Su • Kai-Li Liu • Li-Yan Fu • Yi-Kang Hou • Xiao-Lian Shi • Ying Li • Jian-Jun Mu • Wen-Sheng Chen • Wei Cui • Guo-Qing Zhu • Philip J. Ebenezer • Joseph Francis • Yu-Ming Kang
2019, 35(1): 47-56   [ Abstract]   [ SpringerLink]

Chronic Intracerebroventricular Infusion of Metformin Inhibits Salt-Sensitive Hypertension via Attenuation of Oxidative Stress and Neurohormonal Excitation in Rat Paraventricular Nucleus
Xiao-Jing Yu • Ya-Nan Zhao • Yi-Kang Hou • Hong-Bao Li • Wen-Jie Xia • Hong-Li Gao • Kai-Li Liu • Qing Su • Hui-Yu Yang • Bin Liang • Wen-Sheng Chen • Wei Cui • Ying Li • Guo-Qing Zhu • Zhi-Ming Yang • Yu-Ming Kang
2019, 35(1): 57-66   [ Abstract]   [ SpringerLink]

Angiotensin-Converting Enzyme 2 in the Rostral Ventrolateral Medulla Regulates Cholinergic Signaling and Cardiovascular and Sympathetic Responses in Hypertensive Rats
Yu Deng • Xing Tan • Miao-Ling Li • Wei-Zhong Wang • Yang-Kai Wang
2019, 35(1): 67-78   [ Abstract]   [ SpringerLink]

Chronic Intermittent Hypobaric Hypoxia Ameliorates Renal Vascular Hypertension Through Up-regulating NOS in Nucleus Tractus Solitarii
Na Li • Yue Guan • Yan-Ming Tian • Hui-Jie Ma • Xiangjian Zhang • Yi Zhang • Sheng Wang
2019, 35(1): 79-90   [ Abstract]   [ SpringerLink]

Baroreflex Control of Heart Rate in Mice Overexpressing Human SOD1: Functional Changes in Central and Vagal Efferent Components
Jin Chen • He Gu • Robert D. Wurster • Zixi Cheng
2019, 35(1): 91-97   [ Abstract]   [ SpringerLink]

Reviews

Cellular and Molecular Mechanisms Underlying Arterial Baroreceptor Remodeling in Cardiovascular Diseases and Diabetes
Huiyin Tu • Dongze Zhang • Yu-Long Li
2019, 35(1): 98-112   [ Abstract]   [ SpringerLink]

Next-Generation Tools to Study Autonomic Regulation In Vivo
Snigdha Mukerjee • Eric Lazartigues
2019, 35(1): 113-123   [ Abstract]   [ SpringerLink]

Impaired Hypothalamic Regulation of Sympathetic Outflow in Primary Hypertension
Jing-Jing Zhou • Hui-Jie Ma • Jian-Ying Shao • Hui-Lin Pan • De-Pei Li
2019, 35(1): 124-132   [ Abstract]   [ SpringerLink]

Autonomic Disturbances in Acute Cerebrovascular Disease
Jun Mo • Lei Huang • Jianhua Peng • Umut Ocak • Jianmin Zhang • John H. Zhang
2019, 35(1): 133-144   [ Abstract]   [ SpringerLink]

Cell-Type Identification in the Autonomic Nervous System
Di-Shi Liu • Tian-Le Xu
2019, 35(1): 145-155   [ Abstract]   [ SpringerLink]

Pharmacological Modulation of Vagal Nerve Activity in Cardiovascular Diseases
Longzhu Liu • Ming Zhao • Xiaojiang Yu • Weijin Zang
2019, 35(1): 156-166   [ Abstract]   [ SpringerLink]

Letter to the Editor

Cytoprotective Mechanism of the Novel Gastric Peptide BPC157 in Gastrointestinal Tract and Cultured Enteric Neurons and Glial Cells
Xi-Yu Wang • Meihua Qu • Rui Duan • Dengping Shi • Ling Jin • Jinping Gao • Jackie D. Wood • Junhua Li • Guo-Du Wang
2019, 35(1): 167-170   [ Abstract]   [ SpringerLink]

Perspective

Orthostatic Intolerance and Coagulation Abnormalities: An Update
Wei Quan • Yuchen Wang • Selena Chen • Junbao Du
2019, 35(1): 171-177   [ Abstract]   [ SpringerLink]


Volume 35, Issue. 1, February, 2019

About the cover

The autonomic nervous system integrates the involuntary physiological activities of visceral organs that are vital for survival, controlling the heart rate, blood pressure, breathing, gastrointestinal contraction and secretion, and electrolyte and fluid homeostasis. In this special issue, a number of articles address the underlying neural mechanisms and significance of autonomic dysfunction in the pathogenesis of diseases and provide potential interventions. Yang et al. found that decreased β-cell function is closely associated with the presence of cardiovascular autonomic neuropathy in newly-diagnosed type 2 diabetic patients. The cover image shows the close association between β-cell function and cardiovascular autonomic neuropathy. See pages 25–33. (Cover image provided by Dr. Xubin Yang)