Volume 35, Issue. 4, August, 2019


Original Articles

Aberrant Resting-State Functional Connectivity in the Default Mode Network in Pediatric Bipolar Disorder Patients with and without Psychotic Symptoms
Yuan Zhong • Chun Wang • Weijia Gao • Qian Xiao • Dali Lu • Qing Jiao • Linyan Su • Guangming Lu
2019, 35(4): 581-590   [ Abstract]   [ SpringerLink]

Letters to the Editor

Association of Genetic Polymorphisms with Age at Onset in Han Chinese Patients with Bipolar Disorder
Shao-Hua Hu • Yu-Qing Han • Ting-Ting Mou • Man-Li Huang • Jian-Bo Lai • Chee H Ng • Jing Lu • Qiao-Qiao Lu • Qiu-Yan Lin • Yu-Zhi Zhang • Jian-Bo Hu • Ning Wei • Wei-Juan Xu • Wei-Hua Zhou • Jing-Kai Chen • Chan-Chan Hu • Xiao-Yi Zhou • Shao-Jia Lu • Yi Xu
2019, 35(4): 591-594   [ Abstract]   [ SpringerLink]

Reviews

The Relationship Between Neuroimmunity and Bipolar Disorder: Mechanism and Translational Application
Zhiang Niu • Lu Yang • Xiaohui Wu • Yuncheng Zhu • Jun Chen • Yiru Fang
2019, 35(4): 595-607   [ Abstract]   [ SpringerLink]

Insight

Perspective on Etiology and Treatment of Bipolar Disorders in China: Clinical Implications and Future Directions
Zuowei Wang • Chen Jun • Keming Gao • Haichen Yang  • Yiru Fang
2019, 35(4): 608-612   [ Abstract]   [ SpringerLink]

Original Articles

Increased CXCL13 and CXCR5 in Anterior Cingulate Cortex Contributes to Neuropathic Pain-Related Conditioned Place Aversion
Xiao-Bo Wu • Li-Na He • Bao-Chun Jiang• Xue Wang • Ying Lu • Yong-Jing Gao
2019, 35(4): 613-623   [ Abstract]   [ SpringerLink]

Up-regulation of P2X7 Receptors Contributes to Spinal Microglial Activation and the Development of Pain Induced by BmK-I
Jingjing Zhou • Xiaoxue Zhang • You Zhou1 • Bin Wu • Zhi-Yong Tan
2019, 35(4): 624-636   [ Abstract]   [ SpringerLink]

Thymosin Alpha-1 Inhibits Complete Freund’s Adjuvant-Induced Pain and Production of Microglia-Mediated Pro-inflammatory Cytokines in Spinal Cord
Yunlong Xu • Yanjun Jiang • Lin Wang• Jiahua Huang• Junmao Wen • Hang Lv • Xiaoli Wu• Chaofan Wan • Chuanxin Yu • Wenjie Zhang • Jiaying Zhao • Yinqi Zhou • Yongjun Chen
2019, 35(4): 637-648   [ Abstract]   [ SpringerLink]

Comparative Study of ROCK1 and ROCK2 in Hippocampal Spine Formation and Synaptic Function
Jinglan Yan • Youcan Pan • Xiaoyan Zheng • Chuanan Zhu • Yu Zhang • Guoqi Shi • Lin Yao • Yongjun Chen • Nenggui Xu
2019, 35(4): 649-660   [ Abstract]   [ SpringerLink]

Antidepressant-Like Action of Single Facial Injection of Botulinum Neurotoxin A is Associated with Augmented 5-HT Levels and BDNF/ERK/CREB Pathways in Mouse Brain
Yang Li • Jing Liu • Xu Liu • Cun-Jin Su • Qi-Lin Zhang • Zhi-Hong Wang• Lei-Fang Cao• Xue-Yan Guo• Ya Huang • Weifeng Luo • Tong Liu
2019, 35(4): 661-672   [ Abstract]   [ SpringerLink]

Rac1 Modulates Excitatory Synaptic Transmission in Mouse Retinal Ganglion Cells
Ling-Zhu Li • Ning Yin • Xue-Yan Li• Yanying Miao • Shuo Cheng • Fang Li • Guo-Li Zhao • Shu-Min Zhong • Xin Wang • Xiong-Li Yang • Zhongfeng Wang
2019, 35(4): 673-687   [ Abstract]   [ SpringerLink]

Age-Related Reduction in Cortical Thickness in First-Episode Treatment-Naı¨ve Patients with Schizophrenia
Yin Lin • Mingli Li • Yi Zhou • Wei Deng • Xiaohong Ma • Qiang Wang • Wanjun Guo • Yinfei Li • Lijun Jiang • Xun Hu • Nanyin Zhang • Tao Li
2019, 35(4): 688-696   [ Abstract]   [ SpringerLink]

Medial Preoptic Area Modulates Courtship Ultrasonic Vocalization in Adult Male Mice
Shu-Chen Gao • Yi-Chao Wei • Shao-Ran Wang • Xiao-Hong Xu
2019, 35(4): 697-708   [ Abstract]   [ SpringerLink]

Cortical Organization of Centrifugal Afferents to the Olfactory Bulb: Mono- and Trans-synaptic Tracing with Recombinant Neurotropic Viral Tracers
Pengjie Wen • Xiaoping Rao • Liuying Xu • Zhijian Zhang • Fan Jia • Xiaobin He • Fuqiang Xu
2019, 35(4): 709-723   [ Abstract]   [ SpringerLink]

Liraglutide Ameliorates Hyperhomocysteinemia-Induced Alzheimer-Like Pathology and Memory Deficits in Rats via Multi-molecular Targeting
Yao Zhang• Jia-Zhao Xie • Xiang-Yang Xu • Jun Hu • Teng Xu•Si Jin • Shao-Juan Yang • Jian-Zhi Wang
2019, 35(4): 724-734   [ Abstract]   [ SpringerLink]

Spontaneous Regional Brain Activity in Healthy Individuals is Nonlinearly Modulated by the Interaction of ZNF804A rs1344706 and COMT rs4680 Polymorphisms
Lingling Cui • Fei Wang • Miao Chang • Zhiyang Yin • Guoguang Fan • Yanzhuo Song • Yange Wei • Yixiao Xu • Yifan Zhang • Yanqing Tang • Xiaohong Gong • Ke Xu
2019, 35(4): 735-742   [ Abstract]   [ SpringerLink]

Independent Component Analysis and Graph Theoretical Analysis in Patients with Narcolepsy
Fulong Xiao • Chao Lu • Dianjiang Zhao • Qihong Zou • Liyue Xu • Jing Li • Jun Zhang • Fang Han
2019, 35(4): 743-755   [ Abstract]   [ SpringerLink]

Effect of Apolipoprotein E Genotypes on Huntington’s Disease Phenotypes in a Han Chinese Population
Xiao-Yan Li • Yan-Bin Zhang• Miao Xu• Hong-Rong Cheng • Yi Dong • Wang Ni • Hong-Lei Li • Zhi-Ying Wu
2019, 35(4): 756-762   [ Abstract]   [ SpringerLink]

Letters to the Editor

Selective Targeting of Perirhinal Cortex Projection to Hippocampal CA1 Interneurons
Xiang Li• Yiding Li• Junhui Zhang • Xiaohui Zhang
2019, 35(4): 763-765   [ Abstract]   [ SpringerLink]

Dynamic Alterations in Spontaneous Brain Activity in Mothers: A Resting-State Functional Magnetic Resonance Imaging Study
Kaihua Zhang • Mengxing Wang • Jilei Zhang • Junyao Xie • Xueyun Su  • Xiaoxia Du • Zhong Chen
2019, 35(4): 766-770   [ Abstract]   [ SpringerLink]

Research Highlights

Toll of Mental Disorders: TLR-Mediated Function of the Innate Immune System
Jian-Feng Liu1* • Ruyan Wu1,2 • Jun-Xu Li1*
2019, 35(4): 771-774   [ Abstract]   [ SpringerLink]

The Secret of Fear Memory Attenuation: Facing Fears
Yan-Chen Guo • Tifei Yuan • Ben-Yu Guo
2019, 35(4): 775-777   [ Abstract]   [ SpringerLink]

Correction

Correction to: Expression and Function of Zinc-a2-Glycoprotein
Xin Wei • Xi Liu • Changhong Tan • Lijuan Mo • Hui Wang • Xi Peng • Fen Deng • Lifen Chen
2019, 35(4): 778-779   [ Abstract]   [ SpringerLink]

Correction to: Antidepressant-Like Action of Single Facial Injection of Botulinum Neurotoxin A is Associated with Augmented 5-HT Levels and BDNF/ERK/CREB Pathways in Mouse Brain
Yang Li• Jing Liu • Xu Liu • Cun-Jin Su • Qi-Lin Zhang • Zhi-Hong Wang • Lei-Fang Cao • Xue-Yan Guo • Ya Huang • Weifeng Luo • Tong Liu
2019, 35(4): 779-780   [ Abstract]   [ SpringerLink]


Volume 35, Issue. 4, August, 2019

About the cover

Bipolar disorders (BD) are severe psychiatric diseases that contributed to a significant worldwide disease burden. The etiology of BD is unknown and clinical diagnosis and treatments are difficult. This special topic brings together review and insight on the treatment, administrative, and mechanism of BD. Two original studies report neuroimaging and genetic changes in BD patients. In the cover image, the circle is made up half of the brain tissue and half of the vascular tissue. In the middle of the circle, two tissues are connected by astrocytes to form the blood-brain barrier, which represents the possible neuroimmunology mechanism of the etiology in BD. The division of the circle adopts a structure that similar to Tai-Chi (Yin-Yang) so as to present the completely opposite domain of the clinical symptoms in patients with BD. The cranes represent the psychotic symptoms that BD patients may have. (Cover image provided by Zhiang Niu and Lvchun Cui)