Brain Banking for Research into Neurodegenerative Disorders and Ageing
Claire E. Shepherd1 • Holly Alvendia1,2 • Glenda M. Halliday1,3,*
1Neuroscience Research Australia and the University of New South Wales, Sydney, Australia
2New York University, New York, NY, USA
3Brain and Mind Centre, Sydney Medical School, University of Sydney, Sydney, Australia
Advances in cellular and molecular biology underpin most current therapeutic advances in medicine. Such advances for neurological and neurodegenerative diseases are hindered by the lack of similar specimens. It is becoming increasingly evident that greater access to human brain tissue is necessary to understand both the cellular biology of these diseases and their variation. Research in these areas is vital to the development of viable therapeutic options for these currently untreatable diseases. The development and coordination of human brain specimen collection through brain banks is evolving. This perspective article from the Sydney Brain Bank reviews data concerning the best ways to collect and store material for different research purposes.
Brain banking; Brain donation; Neurodegenerative diseases; Human brain tissue processing