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Current Issue Table of Contents: 15 Volume 37, Issue 11, Novermber, 2021

Impact Factor 5.203*
Journal Citation Reports Q2

About the Cover

The cerebellum is a co-processor of motor and non-motor behaviors through the 'cerebellar connectome', in which the thalamic complex is a relay center. Ma et al. found that the cerebellar interposed nucleus (IpN) only forms functional projections with the thalamic ventrolateral (VL) nucleus but not the centrolateral (CL) nucleus. Interestingly, the IpN–VL projection displays enormous heterogeneity in three-dimensional space. The cover image vividly describes this innervation pattern: the vines derived from the cerebellum wind their way to connect with a lush tree (thalamic complex), and bear fruit only on brown branches (VL) but not on yellow ones (CL). The distribution of fruit is quite uneven: more fruit in some places while few in other places, implying the spatial heterogeneity of cerebello-thalamic projections. The mouse runs eagerly towards the cerebellum and the tree, meaning that cerebello-thalamic projections are essential to motor control. See pages 1529–1541. (Cover art by Drs Zhaoxiang Wang and Ying Shen).

Shumin Duan

Ru-Rong Ji

Editorial Board


Aligned Organization of Synapses and Mitochondria in Auditory Hair Cells
Jing Liu1,2,3 • Shengxiong Wang4,5 • Yan Lu5,6,7,8 • Haoyu Wang5,6,7,8 • Fangfang Wang5 • Miaoxin Qiu4 • Qiwei Xie9 • Hua Han1,2,3 • Yunfeng Hua5,6,7,8 [SpringerLink]

Molecular Sensors of Temperature, Pressure, and Pain with Special Focus on TRPV1, TRPM8, and PIEZO2 Ion Channels
Ru-Rong Ji1,2 • Seok-Yong Lee3 [SpringerLink]

A Breakthrough in Understanding the Rapid Antidepressant Effect of Ketamine Based on Structural Analysis
Hongmei Liu1 • Xiaohui Wu1 • Jun Chen1,3 • Yiru Fang1,2,3 [SpringerLink]

Loss of C9orf72 in Microglia Drives Neuronal Injury by Enhancing Synaptic Pruning in Aged and Alzheimer’s Disease Mice
Mengmeng Wang1,2 • Yuanyuan Jiang1,2 • Zhihui Huang1,2 [SpringerLink]

Modulation of Spike Count Correlations Between Macaque Primary Visual Cortex Neurons by Difficulty of Attentional Task
Qiyi Hu1 • Wenjuan Hu1 • Keyi Liu1 • Xiangdong Bu1 • Lisha Hu1 • Liming Li1 • Xinyu Chai1 • Yao Chen1 [SpringerLink]

Regulation of Axon Initial Segment Diameter by COUP-TFI Fine-tunes Action Potential Generation
Xuanyuan Wu1,2,3 • Haixiang Li1,2,3 • Jiechang Huang1,2,3 • Mengqi Xu1 • Cheng Xiao4 • Shuijin He1 [SpringerLink]

Loss of O-GlcNAcylation on MeCP2 at Threonine 203 Leads to Neurodevelopmental Disorders
Juanxian Cheng1 • Zhe Zhao1 • Liping Chen1 • Ying Li1 • Ruijing Du1 • Yan Wu1 • Qian Zhu1 • Ming Fan1,3 • Xiaotao Duan4 • Haitao Wu1,2,3 [SpringerLink]

Microglial SIRPa Deletion Facilitates Synapse Loss in Preclinical Models of Neurodegeneration
Chongyun Wu1 • Luodan Yang2 • Hannah Youngblood3 • Timon Cheng-Yi Liu1 • Rui Duan [SpringerLink]


A Novel Phagocytic Role of Astrocytes in Activity-dependent Elimination of Mature Excitatory Synapses
Tong Luo • Tian-Ming Gao [SpringerLink]

A Temporal Precision Approach for Deep Transcranial Optogenetics with Non-invasive Surgery
Shanshan Sun • Jiali Shi • Yongjie Wang • Jun Cheng • Zhihui Huang [SpringerLink]

Heteromolecular Plasticity in Striatal Astrocytes
Yi-Hua Chen • Tian-Ming Gao [SpringerLink]

Naturally Occurring Parkinson’s Disease Raises the Need for Nonhuman Primates in Neurodegenerative Diseases Research
Yuxuan Yao • Ji Dai [SpringerLink]

Activated Natural Killer Cells Hit Neurogenesis in the Aging Brain
Angelica Cuapio • Hans-Gustaf Ljunggren [SpringerLink]

STING-ing Pain: How Can Pro-inflammatory Signaling Attenuate Pain?
Wolfgang Liedtke [SpringerLink]

The Parabrachial Nucleus as a Key Regulator of Neuropathic Pain
Zilong Wang • Zhen-Zhong Xu [SpringerLink]

Combination of Biomedical Techniques and Paradigms to Improve Prognostications for Disorders of Consciousness
Ming Song • Jianghong He • Yi Yang • Tianzi Jiang [SpringerLink]

Autologous Transplantation for Parkinson's Disease Patients: Feasibility and Challenge
Qi Zhang • Yanlin Wang • Yukai Wang • Han Liu • Huifang Sun • Zhuoya Wang • Changhe Shi • Jing Yang • Yuming Xu [SpringerLink]

Breakthrough in Structural and Functional Dissection of the Hypothalamo-Neurohypophysial System
Ying Wang • Huamin Xu • Xia Zhang [SpringerLink]

Top-down Modulation of Outcome Processing in Primary Sensory Cortex for Flexible Behavior
Qi Cheng • Chengyu T. Li [SpringerLink]

Brain Energy Improvement as an Emerging Approach for Alzheimer’s Disease Treatment
Xiaoli Pan • Shaoming Sang • Chunjiu Zhong [SpringerLink]


The Risk and Prevention of Novel Coronavirus Pneumonia Infections Among Inpatients in Psychiatric Hospitals
Yuncheng Zhu • Liangliang Chen • Haifeng Ji • Maomao Xi • Yiru Fang • Yi Li [SpringerLink]

Expert Consensus on the Care and Management of Patients with Cognitive Impairment in China
Academy of Cognitive Disorders of China (ACDC) • Yuliang Han • Jianjun Jia • Xia Li • Yang Lv • Xuan Sun • Shanshan Wang • Yongjun Wang • Zhiwen Wang • Jintao Zhang • Jiong Zhou & Yuying Zhou [SpringerLink]

An Overview of the Expert Consensus on the Prevention and Treatment of Gaming Disorder in China (2019 Edition)
Yu-Tao Xiang • Yu Jin • Ling Zhang • Lu Li • Gabor S. Ungvari • Chee H. Ng • Min Zhao & Wei Hao [SpringerLink]

Perspective on Etiology and Treatment of Bipolar Disorders in China: Clinical Implications and Future Directions
Zuowei Wang • Chen Jun • Keming Gao • Haichen Yang • Yiru Fang [SpringerLink]

Standardized Operational Protocol for Human Brain Banking in China
Wenying Qiu • Hanlin Zhang • Aimin Bao • Keqing Zhu • Yue Huang • Xiaoxin Yan • Jing Zhang • Chunjiu Zhong • Yong Shen • Jiangning Zhou • Xiaoying Zheng • Liwei Zhang • Yousheng Shu • Beisha Tang • Zhenxin Zhang • Gang Wang • Ren Zhou • Bing Sun • Changlin Gong • Shumin Duan & Chao Ma [SpringerLink]

Impaired Hypothalamic Regulation of Sympathetic Outflow in Primary Hypertension
Jing-Jing Zhou • Hui-Jie Ma • Jian-Ying Shao • Hui-Lin Pan • De-Pei Li [SpringerLink]

The Risk and Prevention of Novel Coronavirus Pneumonia Infections Among Inpatients in Psychiatric Hospitals
Yuncheng Zhu 1 • Liangliang Chen 2 • Haifeng Ji 2 • Maomao Xi 3 • Yiru Fang 1,5,6 • Yi Li 4 [SpringerLink]

An Overview of Autism Spectrum Disorder, Heterogeneity and Treatment Options OPEN ACCESS
Anne Masi1 • Marilena M. DeMayo1 • Nicholas Glozier1 • Adam J. Guastella1 [SpringerLink]

Pharmacological Modulation of Vagal Nerve Activity in Cardiovascular Diseases
Longzhu Liu • Ming Zhao • Xiaojiang Yu • Weijin Zang* [SpringerLink]

Gene Editing to the Rescue: Reversal of Social Deficits Associated with MECP2 Duplication
Zi-Xian Yu 1,2,3 • Dan-Yang Wang 1,2,3 • Xiao-Hong Xu 1,3 [SpringerLink]

Regulation of Pain and Itch by TRP Channels
Carlene Moore1 • Rupali Gupta1 • Sven-Eric Jordt2 • Yong Chen1,* • Wolfgang B. Liedtke1,2,* [SpringerLink]

Spinal Circuits Transmitting Mechanical Pain and Itch
Bo Duan1,* • Longzhen Cheng2,* • Qiufu Ma3,* [SpringerLink]


Special Issue: Purinergic Signaling in the Central Nervous System in Health and Disease
Guest Editor: Yong Tang, Peter Illes, and Guang-Yin Xu
2020 Vol 36 Issue 11

[PDF] [SpringerLink]

Special Issue:Bipolar Disorders
Guest Editor:Yiru Fang
2019 Vol 35 Issue 4

[PDF] [SpringerLink]

Special Issue: Neurotechniques
Guest Editor: Guo-Qiang Bi
2019 Vol 35 Issue 3

[PDF] [SpringerLink]

Special Issue:Human Brain Bank: Construction and Research
Guest Editor: Chao Ma and Dick F. Swaab
2019 Vol 35 Issue 2

[PDF] [SpringerLink]

Special Issue: Regulation of Autonomic Nervous System
Guest Editor: Qing-Hui Chen
2019 Vol 35 Issue 1

[PDF] [SpringerLink]